"Stupid People"
I was interviewing for a tech support job and had a pretty good rapport going with my interviewer. She asked me what I thought was the worst part of doing tech support work, to which I rather quickly responded "the [expletive] stupid people."
I definitely didn't intend for the [expletive] to make it into the sentence, but it just sort of slipped out, not that "the stupid people" was really a great answer anyway.
In the end, I still got the job. My old boss and I joke about that interview to this day.